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Citalopram vs Meloxicam: side-by-side comparison

Citalopram (Selective serotonin reuptake inhibitor (SSRI)) and Meloxicam (NSAID (preferential COX-2 inhibitor)) belong to different therapeutic classes and are rarely substitutes for each other. The comparison is useful when a single patient is weighing both options for adjacent or overlapping needs.

Property Citalopram Meloxicam
Therapeutic class Selective serotonin reuptake inhibitor (SSRI) NSAID (preferential COX-2 inhibitor)
CAS 59729-33-8 71125-38-7
ATC N06AB04 M01AC06
Molecular weight 324.39 g/mol 351.40 g/mol
Brands with this active ingredient 1 1

What they share

Citalopram and Meloxicam share the common regulatory framework for prescription active ingredients, bioequivalence standards for generics, and pharmacist oversight. Beyond that, points in common are limited.

Key differences

Citalopram acts by a different mechanism than Meloxicam, with indications that barely overlap. Comparing the two is useful when a clinician has mentioned both in the same context or the patient wants to understand why one was prescribed instead of the other.

Mechanisms compared

Citalopram: Le citalopram inhibe sélectivement le transporteur de recapture de la sérotonine, augmentant la disponibilité synaptique de la sérotonine avec une affinité limitée pour les transporteurs de la noradrénaline ou les autres… Meloxicam: Le méloxicam inhibe les cyclo-oxygénases avec une préférence pour la COX-2 aux faibles doses thérapeutiques.

Indications compared

Citalopram: Le citalopram est autorisé dans la dépression caractérisée. Meloxicam: Le méloxicam est autorisé chez l'adulte dans le traitement symptomatique de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante.

Safety profile

Citalopram: Les effets indésirables fréquents comprennent nausées, sécheresse buccale, céphalées, troubles de la fonction sexuelle, troubles du sommeil et augmentation de la sudation. Meloxicam: Les effets indésirables fréquents comprennent troubles digestifs, œdèmes périphériques, hypertension et céphalées.

Questions fréquentes

Is Citalopram better than Meloxicam?

Citalopram and Meloxicam are not "better or worse" — they treat different things. The sensible question is which fits your specific need.

Can Citalopram and Meloxicam be combined?

Whether they can be combined depends on the indications and the interaction profile of each. If both are in a single prescription, the prescriber has weighed it; in self-medication they should never be combined.

Do they have the same side-effect profile?

No — they belong to different classes and have distinct side-effect profiles. Each has its own prescribing information.

Products with Citalopram

Products with Meloxicam

Les informations publiées sur ce site sont fournies à titre documentaire et pédagogique. Elles ne remplacent pas l'avis d'un professionnel de santé qualifié.