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Meloxicam vs Citalopram: side-by-side comparison

Meloxicam (NSAID (preferential COX-2 inhibitor)) and Citalopram (Selective serotonin reuptake inhibitor (SSRI)) belong to different therapeutic classes and are rarely substitutes for each other. The comparison is useful when a single patient is weighing both options for adjacent or overlapping needs.

Property Meloxicam Citalopram
Therapeutic class NSAID (preferential COX-2 inhibitor) Selective serotonin reuptake inhibitor (SSRI)
CAS 71125-38-7 59729-33-8
ATC M01AC06 N06AB04
Molecular weight 351.40 g/mol 324.39 g/mol
Brands with this active ingredient 1 1

What they share

Meloxicam and Citalopram share the common regulatory framework for prescription active ingredients, bioequivalence standards for generics, and pharmacist oversight. Beyond that, points in common are limited.

Key differences

Meloxicam acts by a different mechanism than Citalopram, with indications that barely overlap. Comparing the two is useful when a clinician has mentioned both in the same context or the patient wants to understand why one was prescribed instead of the other.

Mechanisms compared

Meloxicam: Le méloxicam inhibe les cyclo-oxygénases avec une préférence pour la COX-2 aux faibles doses thérapeutiques. Citalopram: Le citalopram inhibe sélectivement le transporteur de recapture de la sérotonine, augmentant la disponibilité synaptique de la sérotonine avec une affinité limitée pour les transporteurs de la noradrénaline ou les autres…

Indications compared

Meloxicam: Le méloxicam est autorisé chez l'adulte dans le traitement symptomatique de l'arthrose, de la polyarthrite rhumatoïde et de la spondylarthrite ankylosante. Citalopram: Le citalopram est autorisé dans la dépression caractérisée.

Safety profile

Meloxicam: Les effets indésirables fréquents comprennent troubles digestifs, œdèmes périphériques, hypertension et céphalées. Citalopram: Les effets indésirables fréquents comprennent nausées, sécheresse buccale, céphalées, troubles de la fonction sexuelle, troubles du sommeil et augmentation de la sudation.

Questions fréquentes

Is Meloxicam better than Citalopram?

Meloxicam and Citalopram are not "better or worse" — they treat different things. The sensible question is which fits your specific need.

Can Meloxicam and Citalopram be combined?

Whether they can be combined depends on the indications and the interaction profile of each. If both are in a single prescription, the prescriber has weighed it; in self-medication they should never be combined.

Do they have the same side-effect profile?

No — they belong to different classes and have distinct side-effect profiles. Each has its own prescribing information.

Products with Meloxicam

Products with Citalopram

Les informations publiées sur ce site sont fournies à titre documentaire et pédagogique. Elles ne remplacent pas l'avis d'un professionnel de santé qualifié.