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Ativan vs Cymbalta: side-by-side comparison

Ativan (Lorazepam) 0.5mg tablet
Ativan
vs
Cymbalta (Duloxetine) 20mg capsule
Cymbalta

Ativan (Anxiolytiques) and Cymbalta (Antidépresseurs) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Ativan Cymbalta
Active ingredient Lorazepam Duloxetine
Manufacturer Pfizer Eli Lilly
Class Anxiolytiques Antidépresseurs
Strengths 0.5mg, 1mg, 2mg 20mg, 30mg, 60mg
Forms tablet, oral concentrate, injection capsule

What's the same

Ativan and Cymbalta are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Ativan belongs to Anxiolytiques while Cymbalta belongs to Antidépresseurs. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Ativan: Le lorazépam se lie au site benzodiazépine du récepteur GABA-A et renforce de façon allostérique la conductance chlorure inhibitrice. Cymbalta: Cymbalta inhibe la recapture synaptique de la sérotonine et de la noradrénaline.

When Ativan is preferred

Ativan est autorisé chez l'adulte dans la prise en charge de courte durée des troubles anxieux et de l'insomnie liée à l'anxiété.

When Cymbalta is preferred

Cymbalta est autorisé dans la dépression caractérisée, le trouble anxieux généralisé, les douleurs neuropathiques périphériques diabétiques, la fibromyalgie et les douleurs musculosquelettiques chroniques.

Questions fréquentes

Is Ativan or Cymbalta better?

Ativan and Cymbalta are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Ativan to Cymbalta?

Switching between Ativan and Cymbalta is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Ativan and Cymbalta have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Ativan comparisons

Les informations publiées sur ce site sont fournies à titre documentaire et pédagogique. Elles ne remplacent pas l'avis d'un professionnel de santé qualifié.