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Ativan vs Cymbalta: side-by-side comparison

Ativan (Lorazepam) 0.5mg tablet
Ativan
vs
Cymbalta (Duloxetine) 20mg capsule
Cymbalta

Ativan (Angstlösende Medikamente) and Cymbalta (Antidepressiva) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Ativan Cymbalta
Active ingredient Lorazepam Duloxetine
Manufacturer Pfizer Eli Lilly
Class Angstlösende Medikamente Antidepressiva
Strengths 0.5mg, 1mg, 2mg 20mg, 30mg, 60mg
Forms tablet, oral concentrate, injection capsule

What's the same

Ativan and Cymbalta are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Ativan belongs to Angstlösende Medikamente while Cymbalta belongs to Antidepressiva. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Ativan: Lorazepam bindet an die Benzodiazepin-Bindungsstelle des GABA-A-Rezeptors und verstärkt allosterisch die hemmende Chloridleitfähigkeit. Cymbalta: Cymbalta hemmt die Wiederaufnahme von Serotonin und Noradrenalin an der Synapse.

When Ativan is preferred

Ativan ist bei Erwachsenen zur Kurzzeitbehandlung von Angststörungen und angstbedingten Schlafstörungen zugelassen.

When Cymbalta is preferred

Cymbalta ist zur Behandlung der Major Depression, der generalisierten Angststörung, diabetischer peripherer neuropathischer Schmerzen, Fibromyalgie und chronischer muskuloskelettaler Schmerzen zugelassen.

Häufig gestellte Fragen

Is Ativan or Cymbalta better?

Ativan and Cymbalta are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Ativan to Cymbalta?

Switching between Ativan and Cymbalta is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Ativan and Cymbalta have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Ativan comparisons

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