Priligy with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Priligy (Dapoxetine). The combination is generally fine at 30mg, 60mg, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Priligy can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Dapoxetine acts on CYP3A4 determines whether Priligy affects contraception. Most agents in Erectile Dysfunction (ED) have no clinically meaningful effect on the pill at 30mg, 60mg.
Practical guidance
According to the prescribing information for Dapoxetine, women on hormonal contraception should review Priligy with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Priligy therapy is the standard mitigation.
Frequently asked questions
Will Priligy make my pill less effective? ▾
Most Erectile Dysfunction (ED) medications at 30mg, 60mg do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Dapoxetine states whether the interaction is meaningful.
Do I need a backup contraceptive on Priligy? ▾
Backup contraception is needed only when there is a documented interaction between Priligy and the contraceptive method. For most users at 30mg, 60mg, no backup is required. The pharmacist confirms whether Dapoxetine interacts with hormonal contraception.
More on Priligy
- With alcoholPriligy and alcohol — is it safe to drink?
- With foodShould Priligy be taken with food?
- Side effectsPriligy side effects: common, rare and warning signs
- Dosage guidePriligy dosage guide: how much to take and when
- OnsetHow fast does Priligy start working?
- DurationHow long does Priligy last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.