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Lexapro vs Synthroid: side-by-side comparison

Lexapro (Escitalopram) 5mg tablet
Lexapro
vs
Synthroid (Levothyroxine) 25mcg tablet
Synthroid

Lexapro (Antidépresseurs) and Synthroid (Hormones et contraception) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Lexapro Synthroid
Active ingredient Escitalopram Levothyroxine
Manufacturer Forest/Allergan AbbVie
Class Antidépresseurs Hormones et contraception
Strengths 5mg, 10mg, 20mg 25mcg, 50mcg, 75mcg, 100mcg, 150mcg
Forms tablet tablet

What's the same

Lexapro and Synthroid are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Lexapro belongs to Antidépresseurs while Synthroid belongs to Hormones et contraception. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Lexapro: Lexapro agit en inhibant sélectivement le transporteur de recapture de la sérotonine (SERT) au niveau de la synapse, augmentant la disponibilité de la sérotonine pour les récepteurs postsynaptiques. Synthroid: La lévothyroxine remplace la thyroxine endogène déficitaire, convertie dans les tissus en hormone active, la triiodothyronine (T3), par les enzymes désiodases.

When Lexapro is preferred

Lexapro est autorisé dans la dépression caractérisée et le trouble anxieux généralisé chez l'adulte, ainsi que chez l'adolescent à partir de 12 ans pour la dépression.

When Synthroid is preferred

Synthroid est autorisé dans l'hypothyroïdie de toute cause (thyroïdite de Hashimoto, post-thyroïdectomie, post-iode radioactif, congénitale), dans le goitre et dans la freination de la TSH après cancer thyroïdien différencié.

Questions fréquentes

Is Lexapro or Synthroid better?

Lexapro and Synthroid are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Lexapro to Synthroid?

Switching between Lexapro and Synthroid is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Lexapro and Synthroid have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Lexapro comparisons

Les informations publiées sur ce site sont fournies à titre documentaire et pédagogique. Elles ne remplacent pas l'avis d'un professionnel de santé qualifié.