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Crestor vs Prilosec: side-by-side comparison

Crestor (Rosuvastatin) 5mg tablet
Crestor
vs
Prilosec (Omeprazole) 10mg delayed-release capsule
Prilosec

Crestor (Médicaments cardiovasculaires) and Prilosec (Médicaments gastro-intestinaux) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Crestor Prilosec
Active ingredient Rosuvastatin Omeprazole
Manufacturer AstraZeneca AstraZeneca / P&G
Class Médicaments cardiovasculaires Médicaments gastro-intestinaux
Strengths 5mg, 10mg, 20mg, 40mg 10mg, 20mg, 40mg
Forms tablet delayed-release capsule, delayed-release tablet, oral suspension

What's the same

Crestor and Prilosec are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Crestor belongs to Médicaments cardiovasculaires while Prilosec belongs to Médicaments gastro-intestinaux. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Crestor: La rosuvastatine inhibe de façon compétitive l'HMG-CoA réductase, enzyme limitante de la synthèse hépatique du cholestérol. Prilosec: L'oméprazole est un promédicament de type benzimidazole substitué, activé dans l'environnement acide de la cellule pariétale gastrique, où il inhibe de façon irréversible l'enzyme H+/K+-ATPase — la pompe à protons respon…

When Crestor is preferred

Crestor est autorisé chez l'adulte dans le traitement de l'hypercholestérolémie primaire et de la dyslipidémie mixte, dans la prévention des événements cardiovasculaires chez les patients à risque élevé et en prévention secondaire.

When Prilosec is preferred

Prilosec est autorisé chez l'adulte et l'enfant dans le traitement du reflux gastro-œsophagien, y compris la cicatrisation de l'œsophagite érosive, de l'ulcère gastroduodénal, dans la prévention des ulcères induits par les AINS, dans le syndrome de Zollinger-Ellison et dans le ca…

Questions fréquentes

Is Crestor or Prilosec better?

Crestor and Prilosec are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Crestor to Prilosec?

Switching between Crestor and Prilosec is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Crestor and Prilosec have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Crestor comparisons

Les informations publiées sur ce site sont fournies à titre documentaire et pédagogique. Elles ne remplacent pas l'avis d'un professionnel de santé qualifié.