GLP-1 receptor agonist
Liraglutide with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Liraglutide (Liraglutide). Most antibiotics do not interfere meaningfully with Liraglutide at 6 mg/mL, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some GLP-1 receptor agonist agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Liraglutide at 6 mg/mL.
Practical guidance
According to the prescribing information for Liraglutide, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Liraglutide is co-administered. Adjusted 6 mg/mL dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Liraglutide during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Liraglutide is metabolised and may need a temporary 6 mg/mL adjustment. The prescribing pharmacist should review any new antibiotic against the existing Liraglutide regimen.
Will antibiotics make Liraglutide stop working? ▾
Most antibiotics do not affect Liraglutide efficacy. Rifampicin and a few others can lower Liraglutide levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Products containing Liraglutide
More on Liraglutide
- With alcoholLiraglutide and alcohol — is it safe to drink?
- With foodShould Liraglutide be taken with food?
- Side effectsLiraglutide side effects: common, rare and warning signs
- Dosage guideLiraglutide dosage guide: how much to take and when
- OnsetHow fast does Liraglutide start working?
- DurationHow long does Liraglutide last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.