Prostaglandin analogue
Bimatoprost with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Bimatoprost (Bimatoprost). The combination is generally fine at 0.01%, 0.03%, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Bimatoprost can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Bimatoprost acts on CYP3A4 determines whether Bimatoprost affects contraception. Most agents in Prostaglandin analogue have no clinically meaningful effect on the pill at 0.01%, 0.03%.
Practical guidance
According to the prescribing information for Bimatoprost, women on hormonal contraception should review Bimatoprost with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Bimatoprost therapy is the standard mitigation.
Frequently asked questions
Will Bimatoprost make my pill less effective? ▾
Most Prostaglandin analogue medications at 0.01%, 0.03% do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Bimatoprost states whether the interaction is meaningful.
Do I need a backup contraceptive on Bimatoprost? ▾
Backup contraception is needed only when there is a documented interaction between Bimatoprost and the contraceptive method. For most users at 0.01%, 0.03%, no backup is required. The pharmacist confirms whether Bimatoprost interacts with hormonal contraception.
Products containing Bimatoprost
More on Bimatoprost
- With alcoholBimatoprost and alcohol — is it safe to drink?
- With foodShould Bimatoprost be taken with food?
- Side effectsBimatoprost side effects: common, rare and warning signs
- Dosage guideBimatoprost dosage guide: how much to take and when
- OnsetHow fast does Bimatoprost start working?
- DurationHow long does Bimatoprost last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.