Prostaglandin analogue
Bimatoprost with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Bimatoprost (Bimatoprost). Most antibiotics do not interfere meaningfully with Bimatoprost at 0.01%, 0.03%, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Prostaglandin analogue agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Bimatoprost at 0.01%, 0.03%.
Practical guidance
According to the prescribing information for Bimatoprost, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Bimatoprost is co-administered. Adjusted 0.01%, 0.03% dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Bimatoprost during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Bimatoprost is metabolised and may need a temporary 0.01%, 0.03% adjustment. The prescribing pharmacist should review any new antibiotic against the existing Bimatoprost regimen.
Will antibiotics make Bimatoprost stop working? ▾
Most antibiotics do not affect Bimatoprost efficacy. Rifampicin and a few others can lower Bimatoprost levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Products containing Bimatoprost
More on Bimatoprost
- With alcoholBimatoprost and alcohol — is it safe to drink?
- With foodShould Bimatoprost be taken with food?
- Side effectsBimatoprost side effects: common, rare and warning signs
- Dosage guideBimatoprost dosage guide: how much to take and when
- OnsetHow fast does Bimatoprost start working?
- DurationHow long does Bimatoprost last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.