What to do if you miss a dose of Wellbutrin
Missing a dose of Wellbutrin (Bupropion) is common — most people will skip a dose at some point during a course. The right action depends on how long since the missed dose and whether Wellbutrin is taken event-driven or daily at 75mg, 100mg, 150mg, 300mg. The wrong action — doubling up — is not recommended.
For daily Wellbutrin
If Wellbutrin is taken daily for a chronic condition, take the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case skip the missed dose and continue normally. According to the prescribing information for Bupropion, two doses should never be taken close together to "make up" for a miss.
For event-driven Wellbutrin
If Wellbutrin is used as needed (not on a fixed schedule), there is no "missed dose" in the conventional sense — simply take the planned dose when needed and observe the recommended gap before re-dosing. Wellbutrin inhibits the reuptake of norepinephrine and dopamine, with much weaker effect on serotonin.
Frequently asked questions
Should I double the dose if I missed Wellbutrin? ▾
No. Doubling doses of Wellbutrin to compensate is not recommended at any 75mg, 100mg, 150mg, 300mg strength and increases the risk of side effects without improving efficacy. Take the next scheduled dose normally.
How many missed doses are too many? ▾
Occasional missed doses of Wellbutrin are usually inconsequential. Repeated missed doses can compromise the therapeutic effect — for chronic conditions like those treated with Anti-Depressants, consistent dosing matters. If adherence is hard, discuss reminders, simpler schedules or alternative formulations with the prescriber.
More on Wellbutrin
- With alcoholWellbutrin and alcohol — is it safe to drink?
- With foodShould Wellbutrin be taken with food?
- Side effectsWellbutrin side effects: common, rare and warning signs
- Dosage guideWellbutrin dosage guide: how much to take and when
- OnsetHow fast does Wellbutrin start working?
- DurationHow long does Wellbutrin last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.