Restoril with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Restoril (Temazepam). The combination is generally fine at 7.5mg, 15mg, 22.5mg, 30mg, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Restoril can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Temazepam acts on CYP3A4 determines whether Restoril affects contraception. Most agents in Sleep Aids and Hypnotics have no clinically meaningful effect on the pill at 7.5mg, 15mg, 22.5mg, 30mg.
Practical guidance
According to the prescribing information for Temazepam, women on hormonal contraception should review Restoril with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Restoril therapy is the standard mitigation.
Frequently asked questions
Will Restoril make my pill less effective? ▾
Most Sleep Aids and Hypnotics medications at 7.5mg, 15mg, 22.5mg, 30mg do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Temazepam states whether the interaction is meaningful.
Do I need a backup contraceptive on Restoril? ▾
Backup contraception is needed only when there is a documented interaction between Restoril and the contraceptive method. For most users at 7.5mg, 15mg, 22.5mg, 30mg, no backup is required. The pharmacist confirms whether Temazepam interacts with hormonal contraception.
More on Restoril
- With alcoholRestoril and alcohol — is it safe to drink?
- With foodShould Restoril be taken with food?
- Side effectsRestoril side effects: common, rare and warning signs
- Dosage guideRestoril dosage guide: how much to take and when
- OnsetHow fast does Restoril start working?
- DurationHow long does Restoril last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.