Ovestin 2mg

Forms and dosages

Ovestin is supplied as 0.1% vaginal cream (with applicator), 0.5mg vaginal ovules (pessaries), and 1mg/2mg oral tablets in some markets. For urogenital atrophy, the typical induction is 1 applicator (0.5mg) of cream daily for 2–3 weeks, then maintenance 1–2 times weekly. Ovules are used similarly. Oral estriol is uncommon because absorption is variable. Cream is applied at bedtime to reduce leakage.

Indications

Ovestin vaginal preparations are approved for treatment and prevention of urogenital atrophy and recurrent urinary tract infections in postmenopausal women, and in some markets for vaginal preparation before pelvic surgery. According to current menopause guidelines in Europe, vaginal estriol is one of two preferred local estrogen options (alongside vaginal estradiol) for women whose primary complaint is vaginal dryness, dyspareunia or recurrent UTIs without significant systemic menopausal symptoms.