Midamor 5mg

Forms and dosages

Midamor is supplied as 5mg oral tablets. As monotherapy, the typical dose is 5–10mg once daily, taken with food to reduce gastrointestinal side effects. In combination with HCTZ, fixed-dose tablets typically contain amiloride 5mg + HCTZ 50mg (older formulation) or amiloride 2.5–5mg + HCTZ 12.5–25mg (modern lower-dose). Take in the morning to limit night-time urination.

Indications

Midamor is approved for hypertension (typically in combination with thiazides), oedema in heart failure or hepatic cirrhosis (in combination), and primary hyperaldosteronism (Liddle syndrome and pseudohyperaldosteronism). According to current hypertension guidelines, amiloride is most useful as a low-dose addition to thiazides to prevent hypokalaemia rather than as monotherapy, with spironolactone preferred when significant aldosterone antagonism is desired (heart failure, resistant hypertension).