Who should not take Livial
A contraindication is a condition under which Livial (Tibolone) should not be taken because the risk outweighs the benefit. Livial has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 2.5mg dosing range.
Absolute contraindications
According to the prescribing information for Tibolone, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Livial can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Tibolone in Livial is rapidly converted to three active metabolites with tissue-selective activity.
Frequently asked questions
Can someone with heart disease take Livial? ▾
Some forms of heart disease are absolute contraindications for Livial, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Livial use under specialist supervision. The prescribing information for Tibolone should be reviewed.
Is Livial safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Livial at adjusted lower 2.5mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Livial
- With alcoholLivial and alcohol — is it safe to drink?
- With foodShould Livial be taken with food?
- Side effectsLivial side effects: common, rare and warning signs
- Dosage guideLivial dosage guide: how much to take and when
- OnsetHow fast does Livial start working?
- DurationHow long does Livial last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.