Coumadin 6mg

Forms and dosages

Coumadin is administered orally once daily at a consistent time. According to the prescribing information, the dose is highly individualised, ranging from less than 1mg to more than 10mg per day, and is determined by international normalised ratio (INR) monitoring. Initial dosing is typically 5mg to 10mg per day for several days, then adjusted based on INR. The therapeutic INR range depends on the indication, typically 2 to 3 in atrial fibrillation and 2.5 to 3.5 in mechanical heart valves.

Indications

Coumadin is approved in adults for the prevention and treatment of venous thromboembolism, including deep vein thrombosis and pulmonary embolism, for the prevention of thromboembolic events in atrial fibrillation, for selected mechanical heart valves and after some cardiac procedures. According to international guidelines, direct oral anticoagulants are now preferred in non-valvular atrial fibrillation in many patients, but Coumadin retains a defined role in valvular and severe renal disease.