Bumex 1mg

Forms and dosages

Bumex is supplied as oral tablets in 0.5, 1 and 2mg strengths. For heart-failure oedema, typical starting dose is 0.5–1mg once or twice daily, titrated based on weight and symptom response. For refractory oedema, doses up to 10mg daily may be used. Bumex is taken in the morning, with the second dose (if used) in the early afternoon to limit night-time urination. Onset of diuresis is within 30–60 minutes.

Indications

Bumex is approved for oedema in heart failure, hepatic cirrhosis or chronic kidney disease, and for refractory oedema unresponsive to other diuretics. According to current heart-failure guidelines, Bumex is a useful alternative when furosemide absorption is variable or the patient is diuretic-resistant. It is also used off-label for hypertension, although thiazides and longer-acting loops are typically preferred first-line.