Desyrel vs Lexapro: side-by-side comparison
Desyrel (Trazodone) and Lexapro (Escitalopram) both belong to the Antidépresseurs class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Desyrel | Lexapro |
|---|---|---|
| Active ingredient | Trazodone | Escitalopram |
| Manufacturer | Various generics | Forest/Allergan |
| Class | Antidépresseurs | Antidépresseurs |
| Strengths | 50mg, 100mg, 150mg, 300mg | 5mg, 10mg, 20mg |
| Forms | tablet | tablet |
What's the same
Desyrel and Lexapro both belong to the Antidépresseurs class and are used for partially overlapping indications. The active ingredients — Trazodone vs Escitalopram — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Trazodone vs Escitalopram), strengths (50mg, 100mg, 150mg, 300mg vs 5mg, 10mg, 20mg), forms (tablet vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Desyrel: La trazodone est classée parmi les antagonistes des récepteurs de la sérotonine et inhibiteurs de sa recapture (SARI). Lexapro: Lexapro agit en inhibant sélectivement le transporteur de recapture de la sérotonine (SERT) au niveau de la synapse, augmentant la disponibilité de la sérotonine pour les récepteurs postsynaptiques.
When Desyrel is preferred
Desyrel (trazodone) est autorisé dans la dépression caractérisée.
When Lexapro is preferred
Lexapro est autorisé dans la dépression caractérisée et le trouble anxieux généralisé chez l'adulte, ainsi que chez l'adolescent à partir de 12 ans pour la dépression.
Questions fréquentes
Is Desyrel or Lexapro better? ▾
There is no single answer. Desyrel and Lexapro both belong to the Antidépresseurs class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Desyrel to Lexapro? ▾
Switching within the Antidépresseurs class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Desyrel and Lexapro have the same side effects? ▾
They share many of the Antidépresseurs class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Desyrel comparisons
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