Celexa vs Desyrel: side-by-side comparison
Celexa (Citalopram) and Desyrel (Trazodone) both belong to the Antidépresseurs class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Celexa | Desyrel |
|---|---|---|
| Active ingredient | Citalopram | Trazodone |
| Manufacturer | Forest Laboratories / AbbVie | Various generics |
| Class | Antidépresseurs | Antidépresseurs |
| Strengths | 10mg, 20mg, 40mg | 50mg, 100mg, 150mg, 300mg |
| Forms | tablet | tablet |
What's the same
Celexa and Desyrel both belong to the Antidépresseurs class and are used for partially overlapping indications. The active ingredients — Citalopram vs Trazodone — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Citalopram vs Trazodone), strengths (10mg, 20mg, 40mg vs 50mg, 100mg, 150mg, 300mg), forms (tablet vs tablet), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Celexa: Le citalopram inhibe sélectivement le transporteur de recapture de la sérotonine, augmentant sa disponibilité synaptique avec une affinité limitée pour les transporteurs de la noradrénaline ou les autres récepteurs. Desyrel: La trazodone est classée parmi les antagonistes des récepteurs de la sérotonine et inhibiteurs de sa recapture (SARI).
When Celexa is preferred
Celexa est autorisé dans la dépression caractérisée.
When Desyrel is preferred
Desyrel (trazodone) est autorisé dans la dépression caractérisée.
Questions fréquentes
Is Celexa or Desyrel better? ▾
There is no single answer. Celexa and Desyrel both belong to the Antidépresseurs class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Celexa to Desyrel? ▾
Switching within the Antidépresseurs class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Celexa and Desyrel have the same side effects? ▾
They share many of the Antidépresseurs class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Celexa comparisons
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