Atypical antidepressant / serotonin modulator
Trazodone and surgery: what to do before and after
Surgery raises specific medication-management questions, and getting the answer right matters because both unintended drug interactions during anaesthesia and abrupt discontinuation of important chronic therapies carry risk. Whether Trazodone (Trazodone) needs to be stopped before surgery, continued through, or paused for a defined window depends on Trazodone and the type of procedure.
Before-surgery decision
For most chronic medications including many Atypical antidepressant / serotonin modulator agents, the surgical team or anaesthetist makes the stop-or-continue decision during pre-op assessment. Considerations include bleeding risk, anaesthesia interactions, the urgency of the underlying condition and the type of procedure. According to most guidelines, surprises are avoided by listing all medications including Trazodone at 50mg, 100mg, 150mg, 300mg on the pre-op form.
After surgery
Post-operative resumption of Trazodone depends on the surgical course, the medication's impact on recovery (e.g. wound healing, gastric tolerance, mobility) and any new prescriptions added after surgery. Trazodone is classified as a serotonin antagonist and reuptake inhibitor (SARI). Resuming on schedule is usually the goal as soon as oral intake and clinical stability allow.
Frequently asked questions
Do I need to stop Trazodone before surgery? ▾
It depends on Trazodone and the procedure. The pre-op assessment is where this is decided, ideally a week or more before surgery. Bring the full medication list including Trazodone at 50mg, 100mg, 150mg, 300mg so the team can advise.
When can I restart Trazodone after surgery? ▾
Resumption timing depends on the procedure, the recovery course and any interactions with new postoperative medications. Many patients restart Trazodone on the day of discharge or earlier; some need a longer pause. The surgical team or prescriber confirms the timing.
Products containing Trazodone
More on Trazodone
- With alcoholTrazodone and alcohol — is it safe to drink?
- With foodShould Trazodone be taken with food?
- Side effectsTrazodone side effects: common, rare and warning signs
- Dosage guideTrazodone dosage guide: how much to take and when
- OnsetHow fast does Trazodone start working?
- DurationHow long does Trazodone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.