Atypical antidepressant / serotonin modulator
Trazodone dosage guide: how much to take and when
Choosing the right dose of Trazodone (Trazodone) is the most important practical decision after starting therapy. Trazodone is supplied as tablet in 50mg, 100mg, 150mg, 300mg, and the right dose for a given person depends on the indication, age, comorbidities and tolerance to the active ingredient Trazodone.
Starting dose and titration
According to the prescribing information, most adults begin Trazodone at the lowest available strength of 50mg, 100mg, 150mg, 300mg and titrate up only if symptom control is insufficient and tolerability is good. Higher doses are reserved for selected cases. Older adults, people with renal or hepatic impairment, and those taking interacting medications should usually start at the lowest dose.
When to adjust
Dose adjustment is guided by symptom response and side effect burden, not by arbitrary schedules. Trazodone is classified as a serotonin antagonist and reuptake inhibitor (SARI). If side effects are limiting at a given dose, going down a step is usually preferred over stopping abruptly. If the response is incomplete after several weeks, a higher dose can be tried under medical supervision.
Frequently asked questions
What is the standard starting dose of Trazodone? ▾
Most adults start Trazodone at the lowest strength of 50mg, 100mg, 150mg, 300mg, with adjustment based on symptom response and tolerance. Older adults and those with reduced kidney or liver function generally start lower. The prescriber decides the exact starting dose for each person.
Can I take a higher dose of Trazodone if it isn't working? ▾
Higher doses of Trazodone should only be used after consulting the prescriber. Doubling on your own is unsafe, especially with active ingredients in the Atypical antidepressant / serotonin modulator class. The prescriber can confirm whether titration is appropriate or whether the medication needs to be changed.
Products containing Trazodone
More on Trazodone
- With alcoholTrazodone and alcohol — is it safe to drink?
- With foodShould Trazodone be taken with food?
- Side effectsTrazodone side effects: common, rare and warning signs
- OnsetHow fast does Trazodone start working?
- DurationHow long does Trazodone last?
- Missed doseWhat to do if you miss a dose of Trazodone
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.