Androgen / anabolic steroid
Testosterone with the birth control pill
Many women of reproductive age take a combined or progestogen-only oral contraceptive while also using a chronic medication such as Testosterone (Testosterone). The combination is generally fine at 1%, 1.62%, but a small number of medications can reduce contraceptive efficacy meaningfully and need either a backup method or a switch.
How Testosterone can affect contraceptive efficacy
Combined and progestogen-only contraceptives are metabolised through CYP3A4. Strong CYP3A4 inducers (some antiepileptics, rifampicin, St John's Wort) lower contraceptive plasma levels and reduce efficacy. Whether Testosterone acts on CYP3A4 determines whether Testosterone affects contraception. Most agents in Androgen / anabolic steroid have no clinically meaningful effect on the pill at 1%, 1.62%.
Practical guidance
According to the prescribing information for Testosterone, women on hormonal contraception should review Testosterone with the prescribing pharmacist or doctor. Where an interaction is documented, additional barrier contraception or switching to a non-oral method (IUD, implant) for the duration of Testosterone therapy is the standard mitigation.
Frequently asked questions
Will Testosterone make my pill less effective? ▾
Most Androgen / anabolic steroid medications at 1%, 1.62% do not affect oral contraceptive efficacy. The exceptions are CYP3A4-inducing drugs and a small number of others. The prescribing information for Testosterone states whether the interaction is meaningful.
Do I need a backup contraceptive on Testosterone? ▾
Backup contraception is needed only when there is a documented interaction between Testosterone and the contraceptive method. For most users at 1%, 1.62%, no backup is required. The pharmacist confirms whether Testosterone interacts with hormonal contraception.
Products containing Testosterone
More on Testosterone
- With alcoholTestosterone and alcohol — is it safe to drink?
- With foodShould Testosterone be taken with food?
- Side effectsTestosterone side effects: common, rare and warning signs
- Dosage guideTestosterone dosage guide: how much to take and when
- OnsetHow fast does Testosterone start working?
- DurationHow long does Testosterone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.