Selective serotonin reuptake inhibitor (SSRI)
What to do if you miss a dose of Sertraline
Missing a dose of Sertraline (Sertraline) is common — most people will skip a dose at some point during a course. The right action depends on how long since the missed dose and whether Sertraline is taken event-driven or daily at 25mg, 50mg, 100mg. The wrong action — doubling up — is not recommended.
For daily Sertraline
If Sertraline is taken daily for a chronic condition, take the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case skip the missed dose and continue normally. According to the prescribing information for Sertraline, two doses should never be taken close together to "make up" for a miss.
For event-driven Sertraline
If Sertraline is used as needed (not on a fixed schedule), there is no "missed dose" in the conventional sense — simply take the planned dose when needed and observe the recommended gap before re-dosing. Sertraline selectively blocks the reuptake of serotonin (5-HT) by the presynaptic neuron, increasing the concentration of serotonin in the synaptic cleft.
Frequently asked questions
Should I double the dose if I missed Sertraline? ▾
No. Doubling doses of Sertraline to compensate is not recommended at any 25mg, 50mg, 100mg strength and increases the risk of side effects without improving efficacy. Take the next scheduled dose normally.
How many missed doses are too many? ▾
Occasional missed doses of Sertraline are usually inconsequential. Repeated missed doses can compromise the therapeutic effect — for chronic conditions like those treated with Selective serotonin reuptake inhibitor (SSRI), consistent dosing matters. If adherence is hard, discuss reminders, simpler schedules or alternative formulations with the prescriber.
Products containing Sertraline
More on Sertraline
- With alcoholSertraline and alcohol — is it safe to drink?
- With foodShould Sertraline be taken with food?
- Side effectsSertraline side effects: common, rare and warning signs
- Dosage guideSertraline dosage guide: how much to take and when
- OnsetHow fast does Sertraline start working?
- DurationHow long does Sertraline last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.