Prostaglandin analogue
Who should not take Latanoprost
A contraindication is a condition under which Latanoprost (Latanoprost) should not be taken because the risk outweighs the benefit. Latanoprost has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 0.005% dosing range.
Absolute contraindications
According to the prescribing information for Latanoprost, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Latanoprost can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Latanoprost is a prodrug ester hydrolysed by corneal esterases to its active free acid, which selectively binds the prostaglandin F (FP) receptor.
Frequently asked questions
Can someone with heart disease take Latanoprost? ▾
Some forms of heart disease are absolute contraindications for Latanoprost, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Latanoprost use under specialist supervision. The prescribing information for Latanoprost should be reviewed.
Is Latanoprost safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Latanoprost at adjusted lower 0.005% doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Latanoprost
More on Latanoprost
- With alcoholLatanoprost and alcohol — is it safe to drink?
- With foodShould Latanoprost be taken with food?
- Side effectsLatanoprost side effects: common, rare and warning signs
- Dosage guideLatanoprost dosage guide: how much to take and when
- OnsetHow fast does Latanoprost start working?
- DurationHow long does Latanoprost last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.