Selective serotonin reuptake inhibitor (SSRI)
Who should not take Escitalopram
A contraindication is a condition under which Escitalopram (Escitalopram) should not be taken because the risk outweighs the benefit. Escitalopram has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 5mg, 10mg, 20mg dosing range.
Absolute contraindications
According to the prescribing information for Escitalopram, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Escitalopram can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Escitalopram selectively inhibits the serotonin reuptake transporter (SERT) at the synaptic cleft, increasing serotonin availability for postsynaptic receptors.
Frequently asked questions
Can someone with heart disease take Escitalopram? ▾
Some forms of heart disease are absolute contraindications for Escitalopram, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Escitalopram use under specialist supervision. The prescribing information for Escitalopram should be reviewed.
Is Escitalopram safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Escitalopram at adjusted lower 5mg, 10mg, 20mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Escitalopram
More on Escitalopram
- With alcoholEscitalopram and alcohol — is it safe to drink?
- With foodShould Escitalopram be taken with food?
- Side effectsEscitalopram side effects: common, rare and warning signs
- Dosage guideEscitalopram dosage guide: how much to take and when
- OnsetHow fast does Escitalopram start working?
- DurationHow long does Escitalopram last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.