Short-acting SSRI (premature ejaculation)
Who should not take Dapoxetine
A contraindication is a condition under which Dapoxetine (Dapoxetine) should not be taken because the risk outweighs the benefit. Dapoxetine has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 30mg, 60mg dosing range.
Absolute contraindications
According to the prescribing information for Dapoxetine, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Dapoxetine can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Dapoxetine selectively blocks the serotonin transporter on the presynaptic neuron, increasing serotonin concentration in the synaptic cleft.
Frequently asked questions
Can someone with heart disease take Dapoxetine? ▾
Some forms of heart disease are absolute contraindications for Dapoxetine, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Dapoxetine use under specialist supervision. The prescribing information for Dapoxetine should be reviewed.
Is Dapoxetine safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Dapoxetine at adjusted lower 30mg, 60mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Dapoxetine
More on Dapoxetine
- With alcoholDapoxetine and alcohol — is it safe to drink?
- With foodShould Dapoxetine be taken with food?
- Side effectsDapoxetine side effects: common, rare and warning signs
- Dosage guideDapoxetine dosage guide: how much to take and when
- OnsetHow fast does Dapoxetine start working?
- DurationHow long does Dapoxetine last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.