Selective serotonin reuptake inhibitor (SSRI)
Who should not take Citalopram
A contraindication is a condition under which Citalopram (Citalopram) should not be taken because the risk outweighs the benefit. Citalopram has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 10mg, 20mg, 40mg dosing range.
Absolute contraindications
According to the prescribing information for Citalopram, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Citalopram can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Citalopram selectively inhibits the serotonin reuptake transporter, increasing synaptic serotonin availability with limited affinity for noradrenaline transporters or other receptors.
Frequently asked questions
Can someone with heart disease take Citalopram? ▾
Some forms of heart disease are absolute contraindications for Citalopram, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Citalopram use under specialist supervision. The prescribing information for Citalopram should be reviewed.
Is Citalopram safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Citalopram at adjusted lower 10mg, 20mg, 40mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
Products containing Citalopram
More on Citalopram
- With alcoholCitalopram and alcohol — is it safe to drink?
- With foodShould Citalopram be taken with food?
- Side effectsCitalopram side effects: common, rare and warning signs
- Dosage guideCitalopram dosage guide: how much to take and when
- OnsetHow fast does Citalopram start working?
- DurationHow long does Citalopram last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.