Who should not take Yaz
A contraindication is a condition under which Yaz (Drospirenone/Ethinylestradiol) should not be taken because the risk outweighs the benefit. Yaz has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 3mg/0.02mg dosing range.
Absolute contraindications
According to the prescribing information for Drospirenone, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Yaz can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Yaz prevents pregnancy through three mechanisms: ovulation suppression (the dominant effect), thickening of cervical mucus to impede sperm transit, and changes in endometrial receptivity.
Frequently asked questions
Can someone with heart disease take Yaz? ▾
Some forms of heart disease are absolute contraindications for Yaz, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Yaz use under specialist supervision. The prescribing information for Drospirenone should be reviewed.
Is Yaz safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Yaz at adjusted lower 3mg/0.02mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Yaz
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.