Who should not take Tadalafil
A contraindication is a condition under which Tadalafil (Tadalafil) should not be taken because the risk outweighs the benefit. Tadalafil has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 5mg, 10mg, 20mg dosing range.
Absolute contraindications
According to the prescribing information for Tadalafil, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Tadalafil can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. The mechanism is identical to original Cialis: tadalafil selectively inhibits PDE5 in penile and vascular smooth muscle, allowing cyclic GMP produced during sexual arousal to accumulate.
Frequently asked questions
Can someone with heart disease take Tadalafil? ▾
Some forms of heart disease are absolute contraindications for Tadalafil, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Tadalafil use under specialist supervision. The prescribing information for Tadalafil should be reviewed.
Is Tadalafil safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Tadalafil at adjusted lower 5mg, 10mg, 20mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Tadalafil
- With alcoholTadalafil and alcohol — is it safe to drink?
- With foodShould Tadalafil be taken with food?
- Side effectsTadalafil side effects: common, rare and warning signs
- Dosage guideTadalafil dosage guide: how much to take and when
- OnsetHow fast does Tadalafil start working?
- DurationHow long does Tadalafil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.