Skin side effects of Prometrium: rash, dryness, photosensitivity
Skin reactions are among the most visible side effects of medication and range from minor cosmetic concerns to medical emergencies. Prometrium (Progesterone) at 100mg, 200mg may produce a range of skin effects depending on Progesterone; this page covers what is typical, what is rare, and what calls for stopping the medication.
Common skin effects of Prometrium
According to the prescribing information for Progesterone, common skin reactions include mild rash, dryness, mild itching, transient flushing and (for some agents) photosensitivity that makes the skin more sensitive to UV. Progesterone in Prometrium binds to progesterone receptors and modulates gene expression in reproductive and other tissues. Most are mild, appear in the first weeks and resolve without intervention or with simple measures (moisturiser, sunscreen).
Serious skin reactions
Severe skin reactions — Stevens-Johnson syndrome, toxic epidermal necrolysis, drug-induced hypersensitivity syndrome — are rare but life-threatening. Warning signs are a rash with fever, mucosal involvement (mouth, eyes), skin peeling, or rapidly spreading rash. Any of these on Prometrium at 100mg, 200mg is a medical emergency and reason to stop the medication and seek immediate care.
Frequently asked questions
Is a rash on Prometrium dangerous? ▾
Most rashes on Prometrium at 100mg, 200mg are mild and resolve. A rash with fever, mucosal involvement, blistering or rapid spread is not — it requires emergency evaluation and stopping the medication.
Can Prometrium cause sunburn or photosensitivity? ▾
Some medications including a subset of Hormones and Birth Control agents increase UV sensitivity, making sunburn occur faster. The prescribing information for Progesterone lists this when documented. Sunscreen and avoiding peak sun exposure manage the risk.
More on Prometrium
- With alcoholPrometrium and alcohol — is it safe to drink?
- With foodShould Prometrium be taken with food?
- Side effectsPrometrium side effects: common, rare and warning signs
- Dosage guidePrometrium dosage guide: how much to take and when
- OnsetHow fast does Prometrium start working?
- DurationHow long does Prometrium last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.