What to do if you miss a dose of Plavix

Missing a dose of Plavix (Clopidogrel) is common — most people will skip a dose at some point during a course. The right action depends on how long since the missed dose and whether Plavix is taken event-driven or daily at 75mg, 300mg. The wrong action — doubling up — is not recommended.

For daily Plavix

If Plavix is taken daily for a chronic condition, take the missed dose as soon as you remember, unless it is almost time for the next scheduled dose. In that case skip the missed dose and continue normally. According to the prescribing information for Clopidogrel, two doses should never be taken close together to "make up" for a miss.

For event-driven Plavix

If Plavix is used as needed (not on a fixed schedule), there is no "missed dose" in the conventional sense — simply take the planned dose when needed and observe the recommended gap before re-dosing. After absorption, clopidogrel is converted in the liver to an active metabolite that irreversibly binds the P2Y12 ADP receptor on platelets.

Frequently asked questions

Should I double the dose if I missed Plavix? ▾

No. Doubling doses of Plavix to compensate is not recommended at any 75mg, 300mg strength and increases the risk of side effects without improving efficacy. Take the next scheduled dose normally.

How many missed doses are too many? ▾

Occasional missed doses of Plavix are usually inconsequential. Repeated missed doses can compromise the therapeutic effect — for chronic conditions like those treated with Cardiovascular Medications, consistent dosing matters. If adherence is hard, discuss reminders, simpler schedules or alternative formulations with the prescriber.

More on Plavix

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.