Who should not take Plan B
A contraindication is a condition under which Plan B (Levonorgestrel) should not be taken because the risk outweighs the benefit. Plan B has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 1.5mg dosing range.
Absolute contraindications
According to the prescribing information for Levonorgestrel, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Plan B can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Plan B's primary mechanism is delaying or preventing ovulation when taken before the LH surge.
Frequently asked questions
Can someone with heart disease take Plan B? ▾
Some forms of heart disease are absolute contraindications for Plan B, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Plan B use under specialist supervision. The prescribing information for Levonorgestrel should be reviewed.
Is Plan B safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Plan B at adjusted lower 1.5mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Plan B
- With alcoholPlan B and alcohol — is it safe to drink?
- With foodShould Plan B be taken with food?
- Side effectsPlan B side effects: common, rare and warning signs
- Dosage guidePlan B dosage guide: how much to take and when
- OnsetHow fast does Plan B start working?
- DurationHow long does Plan B last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.