Who should not take Addyi
A contraindication is a condition under which Addyi (Flibanserin) should not be taken because the risk outweighs the benefit. Addyi has both absolute contraindications (do not use) and relative cautions (use only after careful review). This page summarises both at the 100mg dosing range.
Absolute contraindications
According to the prescribing information for Flibanserin, absolute contraindications typically include severe allergic reactions to the active ingredient or excipients, severe hepatic or renal impairment, certain cardiovascular conditions, and concurrent use of specific interacting medications. The exact list depends on the molecule and is detailed in the official label.
Relative cautions
Relative cautions are situations where Addyi can be used but with extra monitoring, dose reduction or alternative considered. These often include mild-to-moderate organ impairment, age extremes, multiple comorbidities, and complex medication regimens. Sexual desire is modulated by complex central nervous system pathways involving serotonin (generally inhibitory) and dopamine and norepinephrine (generally excitatory).
Frequently asked questions
Can someone with heart disease take Addyi? ▾
Some forms of heart disease are absolute contraindications for Addyi, particularly with nitrate use or recent cardiovascular events. Stable, well-controlled cardiovascular disease may allow Addyi use under specialist supervision. The prescribing information for Flibanserin should be reviewed.
Is Addyi safe with kidney problems? ▾
Mild to moderate kidney impairment usually allows Addyi at adjusted lower 100mg doses. Severe kidney failure is often a contraindication or requires substantial dose reduction. The prescriber decides based on lab results and concurrent medications.
More on Addyi
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.