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Plan B vs Acyclovir: side-by-side comparison

Plan B (Levonorgestrel) 1.5mg tablet
Plan B
vs
Acyclovir 200mg tablet
Acyclovir

Plan B (Hormones and Birth Control) and Acyclovir (Antiviral Medications) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Plan B Acyclovir
Active ingredient Levonorgestrel Acyclovir
Manufacturer Foundation Consumer Healthcare Various
Class Hormones and Birth Control Antiviral Medications
Strengths 1.5mg 200mg, 400mg, 800mg
Forms tablet tablet, capsule, oral suspension, topical cream

What's the same

Plan B and Acyclovir are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Plan B belongs to Hormones and Birth Control while Acyclovir belongs to Antiviral Medications. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Plan B: Plan B's primary mechanism is delaying or preventing ovulation when taken before the LH surge. Acyclovir: Acyclovir is a guanosine analogue selectively phosphorylated by viral thymidine kinase to its monophosphate form, then by cellular kinases to acyclovir triphosphate.

When Plan B is preferred

Plan B is indicated for emergency contraception after unprotected intercourse or known/suspected contraceptive failure, in women of reproductive age.

When Acyclovir is preferred

Acyclovir is approved in adults and children for the treatment of herpes simplex virus infections, including genital herpes (initial and recurrent episodes), suppressive therapy of recurrent genital herpes, herpes labialis, mucocutaneous herpes simplex in immunocompromised patien…

Frequently asked questions

Is Plan B or Acyclovir better?

Plan B and Acyclovir are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Plan B to Acyclovir?

Switching between Plan B and Acyclovir is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Plan B and Acyclovir have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Plan B comparisons

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.