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Levonorgestrel vs Finasteride: side-by-side comparison

Levonorgestrel (Synthetic progestin (emergency contraception)) and Finasteride (5-alpha-reductase inhibitor (type II)) belong to different therapeutic classes and are rarely substitutes for each other. The comparison is useful when a single patient is weighing both options for adjacent or overlapping needs.

Property Levonorgestrel Finasteride
Therapeutic class Synthetic progestin (emergency contraception) 5-alpha-reductase inhibitor (type II)
CAS 797-63-7 98319-26-7
ATC G03AC03 G04CB01
Molecular weight 312.5 g/mol 372.5 g/mol
Brands with this active ingredient 1 1

What they share

Levonorgestrel and Finasteride share the common regulatory framework for prescription active ingredients, bioequivalence standards for generics, and pharmacist oversight. Beyond that, points in common are limited.

Key differences

Levonorgestrel acts by a different mechanism than Finasteride, with indications that barely overlap. Comparing the two is useful when a clinician has mentioned both in the same context or the patient wants to understand why one was prescribed instead of the other.

Mechanisms compared

Levonorgestrel: In emergency contraception, levonorgestrel works primarily by delaying or inhibiting ovulation when taken before the LH surge. Finasteride: Finasteride binds with high affinity to 5-alpha-reductase type II, blocking the conversion of testosterone into DHT.

Indications compared

Levonorgestrel: Levonorgestrel is approved for emergency contraception (single 1.5mg dose), regular oral contraception (combined with ethinylestradiol or as progestin-only), and as the active component of hormonal intrauterine devices f… Finasteride: Finasteride is approved at 5mg per day for the treatment of benign prostatic hyperplasia in adult men, where it reduces prostate volume, improves urinary flow and reduces the risk of acute urinary retention and need for…

Safety profile

Levonorgestrel: Common adverse effects of emergency contraceptive use include nausea, headache, fatigue, dizziness, breast tenderness and menstrual cycle changes. Finasteride: Common adverse effects include sexual side effects (decreased libido, erectile dysfunction, ejaculation disorders) reported in approximately 1-3% of men in clinical trials.

Frequently asked questions

Is Levonorgestrel better than Finasteride?

Levonorgestrel and Finasteride are not "better or worse" — they treat different things. The sensible question is which fits your specific need.

Can Levonorgestrel and Finasteride be combined?

Whether they can be combined depends on the indications and the interaction profile of each. If both are in a single prescription, the prescriber has weighed it; in self-medication they should never be combined.

Do they have the same side-effect profile?

No — they belong to different classes and have distinct side-effect profiles. Each has its own prescribing information.

Products with Levonorgestrel

Products with Finasteride

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.