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Finasteride vs Levonorgestrel: side-by-side comparison

Finasteride (5-alpha-reductase inhibitor (type II)) and Levonorgestrel (Synthetic progestin (emergency contraception)) belong to different therapeutic classes and are rarely substitutes for each other. The comparison is useful when a single patient is weighing both options for adjacent or overlapping needs.

Property Finasteride Levonorgestrel
Therapeutic class 5-alpha-reductase inhibitor (type II) Synthetic progestin (emergency contraception)
CAS 98319-26-7 797-63-7
ATC G04CB01 G03AC03
Molecular weight 372.5 g/mol 312.5 g/mol
Brands with this active ingredient 1 1

What they share

Finasteride and Levonorgestrel share the common regulatory framework for prescription active ingredients, bioequivalence standards for generics, and pharmacist oversight. Beyond that, points in common are limited.

Key differences

Finasteride acts by a different mechanism than Levonorgestrel, with indications that barely overlap. Comparing the two is useful when a clinician has mentioned both in the same context or the patient wants to understand why one was prescribed instead of the other.

Mechanisms compared

Finasteride: Finasteride binds with high affinity to 5-alpha-reductase type II, blocking the conversion of testosterone into DHT. Levonorgestrel: In emergency contraception, levonorgestrel works primarily by delaying or inhibiting ovulation when taken before the LH surge.

Indications compared

Finasteride: Finasteride is approved at 5mg per day for the treatment of benign prostatic hyperplasia in adult men, where it reduces prostate volume, improves urinary flow and reduces the risk of acute urinary retention and need for… Levonorgestrel: Levonorgestrel is approved for emergency contraception (single 1.5mg dose), regular oral contraception (combined with ethinylestradiol or as progestin-only), and as the active component of hormonal intrauterine devices f…

Safety profile

Finasteride: Common adverse effects include sexual side effects (decreased libido, erectile dysfunction, ejaculation disorders) reported in approximately 1-3% of men in clinical trials. Levonorgestrel: Common adverse effects of emergency contraceptive use include nausea, headache, fatigue, dizziness, breast tenderness and menstrual cycle changes.

Frequently asked questions

Is Finasteride better than Levonorgestrel?

Finasteride and Levonorgestrel are not "better or worse" — they treat different things. The sensible question is which fits your specific need.

Can Finasteride and Levonorgestrel be combined?

Whether they can be combined depends on the indications and the interaction profile of each. If both are in a single prescription, the prescriber has weighed it; in self-medication they should never be combined.

Do they have the same side-effect profile?

No — they belong to different classes and have distinct side-effect profiles. Each has its own prescribing information.

Products with Finasteride

Products with Levonorgestrel

The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.