Antibiotics with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Antibiotics (Antibiotics). Most antibiotics do not interfere meaningfully with Amoxicillin, Azithromycin, Ciprofloxacin, Clavulanate, Doxycycline at 250mg, 500mg, 875mg, 500/125mg, 875/125mg, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Antibiotics agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Amoxicillin, Azithromycin, Ciprofloxacin, Clavulanate, Doxycycline at 250mg, 500mg, 875mg, 500/125mg, 875/125mg.
Practical guidance
According to the prescribing information for Amoxicillin, Azithromycin, Ciprofloxacin, Clavulanate, Doxycycline, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Antibiotics is co-administered. Adjusted 250mg, 500mg, 875mg, 500/125mg, 875/125mg dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Antibiotics during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Amoxicillin, Azithromycin, Ciprofloxacin, Clavulanate, Doxycycline is metabolised and may need a temporary 250mg, 500mg, 875mg, 500/125mg, 875/125mg adjustment. The prescribing pharmacist should review any new antibiotic against the existing Antibiotics regimen.
Will antibiotics make Antibiotics stop working? ▾
Most antibiotics do not affect Antibiotics efficacy. Rifampicin and a few others can lower Amoxicillin, Azithromycin, Ciprofloxacin, Clavulanate, Doxycycline levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Medications in Antibiotics
More on Antibiotics
- With alcoholAntibiotics and alcohol — is it safe to drink?
- With foodShould Antibiotics be taken with food?
- Side effectsAntibiotics side effects: common, rare and warning signs
- For older adultsAntibiotics after 60: doses and safety in older adults
- For womenAntibiotics for women: indications and considerations
- For menAntibiotics for men: indications and considerations
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.