Anti-anxiety Medications with vitamins, minerals and herbal supplements
Supplements are widely used and rarely disclosed to the prescriber, which makes them a common source of unrecognised interactions with Anti-anxiety Medications (Anti-anxiety Medications). Many supplements are inert or harmless, but a small number — particularly herbal extracts and high-dose vitamins — can affect how Alprazolam, Buspirone, Clonazepam, Lorazepam works at 0.5mg, 1mg, 2mg, 5mg, 7.5mg.
High-priority supplement interactions
St John's Wort is the herbal supplement most often flagged for interactions because it strongly induces CYP3A4 and reduces plasma levels of many medications including several Anti-anxiety Medications agents. Grapefruit-extract supplements work in the opposite direction. High-dose vitamin K affects anticoagulants. Calcium and iron can chelate certain antibiotics.
Practical disclosure
According to the prescribing information for Alprazolam, Buspirone, Clonazepam, Lorazepam, the medication list reviewed by the pharmacist should always include supplements. Most multivitamins at standard doses do not interact meaningfully with Anti-anxiety Medications at 0.5mg, 1mg, 2mg, 5mg, 7.5mg, but anything herbal, anything single-ingredient at high dose, and anything new started recently is worth flagging.
Frequently asked questions
Are vitamins safe with Anti-anxiety Medications? ▾
Standard-dose multivitamins are usually fine with Anti-anxiety Medications at 0.5mg, 1mg, 2mg, 5mg, 7.5mg. High-dose single vitamins (e.g. vitamin K, large doses of vitamin E) can interact with specific medication classes; the pharmacist confirms whether these matter for Alprazolam, Buspirone, Clonazepam, Lorazepam.
Should I tell the pharmacist about herbal supplements? ▾
Yes — particularly St John's Wort, ginseng, ginkgo, garlic extract and any concentrated herbal formulation. Several of these have meaningful interactions with prescription medications including some agents in the Anti-anxiety Medications class.
Medications in Anti-anxiety Medications
More on Anti-anxiety Medications
- With alcoholAnti-anxiety Medications and alcohol — is it safe to drink?
- With foodShould Anti-anxiety Medications be taken with food?
- Side effectsAnti-anxiety Medications side effects: common, rare and warning signs
- For older adultsAnti-anxiety Medications after 60: doses and safety in older adults
- For womenAnti-anxiety Medications for women: indications and considerations
- For menAnti-anxiety Medications for men: indications and considerations
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.