Allergy and Antihistamines with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Allergy and Antihistamines (Allergy and Antihistamines). Most antibiotics do not interfere meaningfully with Cetirizine, Fexofenadine, Loratadine at 30mg, 60mg, 120mg, 180mg, 5mg, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Allergy and Antihistamines agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Cetirizine, Fexofenadine, Loratadine at 30mg, 60mg, 120mg, 180mg, 5mg.
Practical guidance
According to the prescribing information for Cetirizine, Fexofenadine, Loratadine, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Allergy and Antihistamines is co-administered. Adjusted 30mg, 60mg, 120mg, 180mg, 5mg dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Allergy and Antihistamines during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Cetirizine, Fexofenadine, Loratadine is metabolised and may need a temporary 30mg, 60mg, 120mg, 180mg, 5mg adjustment. The prescribing pharmacist should review any new antibiotic against the existing Allergy and Antihistamines regimen.
Will antibiotics make Allergy and Antihistamines stop working? ▾
Most antibiotics do not affect Allergy and Antihistamines efficacy. Rifampicin and a few others can lower Cetirizine, Fexofenadine, Loratadine levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Medications in Allergy and Antihistamines
More on Allergy and Antihistamines
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- For older adultsAllergy and Antihistamines after 60: doses and safety in older adults
- For womenAllergy and Antihistamines for women: indications and considerations
- For menAllergy and Antihistamines for men: indications and considerations
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