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Voltaren vs Lexapro: side-by-side comparison

Voltaren (Diclofenac) 25mg tablet
Voltaren
vs
Lexapro (Escitalopram) 5mg tablet
Lexapro

Voltaren (Schmerzmedikamente) and Lexapro (Antidepressiva) belong to different therapeutic classes and are rarely interchangeable. This page compares the medications' purposes, mechanisms and the situations where each is used.

Property Voltaren Lexapro
Active ingredient Diclofenac Escitalopram
Manufacturer Novartis Forest/Allergan
Class Schmerzmedikamente Antidepressiva
Strengths 25mg, 50mg, 75mg, 100mg 5mg, 10mg, 20mg
Forms tablet, delayed-release tablet, topical gel, suppository tablet

What's the same

Voltaren and Lexapro are used in very different patients, and the points in common are limited. The main shared element is that both meet regulatory standards for efficacy and safety and benefit from pharmacist oversight.

Key differences

Voltaren belongs to Schmerzmedikamente while Lexapro belongs to Antidepressiva. Indications, mechanisms and target populations differ. The comparison is most useful when a clinician has mentioned both medications and the patient wants to understand where each fits.

Mechanism and action

Voltaren: Diclofenac hemmt reversibel die Cyclooxygenase-Enzyme COX-1 und COX-2, mit etwas stärkerer Selektivität für COX-2 als Ibuprofen und Naproxen. Lexapro: Lexapro wirkt durch selektive Hemmung des Serotonin-Wiederaufnahmetransporters (SERT) an der Synapse und erhöht so die Verfügbarkeit von Serotonin für postsynaptische Rezeptoren.

When Voltaren is preferred

Voltaren ist bei Erwachsenen zur Behandlung von Arthrose, rheumatoider Arthritis, ankylosierender Spondylitis, akuten muskuloskelettalen Schmerzen, postoperativen Schmerzen, primärer Dysmenorrhoe, akuter Migräne und Ureterkolik zugelassen.

When Lexapro is preferred

Lexapro ist bei Erwachsenen und Jugendlichen ab 12 Jahren (Depression) sowie bei Erwachsenen (generalisierte Angststörung) zur Behandlung von Major Depression und generalisierter Angststörung zugelassen.

Häufig gestellte Fragen

Is Voltaren or Lexapro better?

Voltaren and Lexapro are not interchangeable — they treat different conditions. Asking which is "better" is meaningful only when a clinician has weighed both for the same specific clinical scenario.

Can I switch from Voltaren to Lexapro?

Switching between Voltaren and Lexapro is rarely an appropriate decision since they belong to different classes and treat different conditions. The real question is usually whether the diagnosis calls for one medication or the other — which the prescriber resolves.

Do Voltaren and Lexapro have the same side effects?

No — they belong to different classes and have distinct side-effect profiles. Each medication has its own prescribing information.

More Voltaren comparisons

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