Voltaren vs Celebrex: side-by-side comparison
Voltaren (Diclofenac) and Celebrex (Celecoxib) both belong to the Schmerzmedikamente class. They share clinical context but use different active ingredients. The choice between them depends on mechanism nuances, side-effect profile and individual response.
| Property | Voltaren | Celebrex |
|---|---|---|
| Active ingredient | Diclofenac | Celecoxib |
| Manufacturer | Novartis | Pfizer |
| Class | Schmerzmedikamente | Schmerzmedikamente |
| Strengths | 25mg, 50mg, 75mg, 100mg | 50mg, 100mg, 200mg, 400mg |
| Forms | tablet, delayed-release tablet, topical gel, suppository | capsule |
What's the same
Voltaren and Celebrex both belong to the Schmerzmedikamente class and are used for partially overlapping indications. The active ingredients — Diclofenac vs Celecoxib — share the same therapeutic approach, so many safety and management points carry across both.
Key differences
Meaningful differences are in active ingredient (Diclofenac vs Celecoxib), strengths (25mg, 50mg, 75mg, 100mg vs 50mg, 100mg, 200mg, 400mg), forms (tablet, delayed-release tablet, topical gel, suppository vs capsule), and the mechanism, half-life and side-effect nuances that distinguish members of the class.
Mechanism and action
Voltaren: Diclofenac hemmt reversibel die Cyclooxygenase-Enzyme COX-1 und COX-2, mit etwas stärkerer Selektivität für COX-2 als Ibuprofen und Naproxen. Celebrex: Celecoxib hemmt selektiv die COX-2, die induzierbare Cyclooxygenase-Isoform, die an Entzündungsorten hochreguliert ist, während die konstitutive COX-1, die die gastrale Mukosa und die Thrombozytenaggregation aufrechterhä…
When Voltaren is preferred
Voltaren ist bei Erwachsenen zur Behandlung von Arthrose, rheumatoider Arthritis, ankylosierender Spondylitis, akuten muskuloskelettalen Schmerzen, postoperativen Schmerzen, primärer Dysmenorrhoe, akuter Migräne und Ureterkolik zugelassen.
When Celebrex is preferred
Celebrex ist bei Erwachsenen zugelassen für die Behandlung von Arthrose, rheumatoider Arthritis, juveniler idiopathischer Arthritis (in einigen Märkten), ankylosierender Spondylitis, primärer Dysmenorrhoe und akuten Schmerzen.
Häufig gestellte Fragen
Is Voltaren or Celebrex better? ▾
There is no single answer. Voltaren and Celebrex both belong to the Schmerzmedikamente class but differ in mechanism nuances, half-life and side-effect profile. Preference depends on the patient, the prescriber and prior response to other therapies.
Can I switch from Voltaren to Celebrex? ▾
Switching within the Schmerzmedikamente class is done under supervision, typically using equivalent doses and a follow-up period to confirm response and tolerance. It is not a self-directed decision.
Do Voltaren and Celebrex have the same side effects? ▾
They share many of the Schmerzmedikamente class side effects, with differences from mechanism and dose. Each medication's prescribing information lists specifics.
More Voltaren comparisons
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