Caverject vs Alprostadil: are they the same?
Caverject is a commercial brand whose active ingredient is exactly Alprostadil. This page explains what that means in practice: where they differ (brand, manufacturer, price, available strengths), why they are clinically equivalent, and when the brand or an authorised generic is the better choice.
Are they the same?
Yes — Caverject contains Alprostadil as its active ingredient. Talking about "Caverject" in clinical terms is the same as talking about Alprostadil at the dose strengths 10mcg, 20mcg, 40mcg. The differences from the authorised generic are brand, manufacturer (Pfizer), excipients, tablet appearance and price — not the active molecule itself.
When Caverject is used
카베젝트는 성인 남성에서 혈관성, 신경성, 심인성 또는 혼합 원인의 발기부전 치료에 승인되어 있습니다. 전립선절제술 후 음경 재활, PDE5 억제제 실패자 또는 사용 불가 환자, 경구 치료에 심혈관계 금기가 있는 환자에서 폭넓게 사용됩니다. 현행 ED 가이드라인에 따르면 카베젝트는 경구 PDE5 억제제 다음의 2차 치료지만 선별된 환자군에서는 1차 치료로 사용됩니다.
Mechanisms compared
Because they share the same active ingredient, the mechanism is identical: 알프로스타딜은 음경해면체 평활근의 프로스타글란딘 E 수용체에 결합하여, PDE5 억제제가 사용하는 산화질소 경로와는 독립적으로 cAMP 매개의 해면체 평활근 이완을 유도합니다.
Brand or generic — which to choose?
For most patients, authorised generics of Alprostadil are clinically equivalent substitutes for Caverject and typically cost substantially less. The practical differences are manufacturer, excipients (rarely matters except in specific sensitivities), tablet appearance and price. The brand is preferred by some patients for personal reasons or insurance coverage; the generic is the default when cost matters.
자주 묻는 질문
Is Caverject the same as Alprostadil? ▾
Clinically yes — Caverject is the brand and Alprostadil is its active ingredient. At equivalent doses (10mcg, 20mcg, 40mcg) they produce the same effect. The difference is brand, manufacturer (Pfizer) and price.
Is generic Alprostadil as effective as Caverject? ▾
Yes. Authorised generics of Alprostadil must demonstrate bioequivalence to the brand. The active substance is the same; average effect is the same. Price is usually substantially lower.
Why does Caverject cost more than generic Alprostadil? ▾
The price difference reflects originator development costs, brand recognition and competition among generic manufacturers. The molecule is identical; the cost is not.
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