Androgen / anabolic steroid
Testosterone with antibiotics: interactions and safety
Antibiotic courses are common, short-term and often combined with chronic medications such as Testosterone (Testosterone). Most antibiotics do not interfere meaningfully with Testosterone at 1%, 1.62%, but a few classes do, and a small number of combinations are best avoided.
Common antibiotic interactions
Macrolides (clarithromycin, erythromycin) and certain antifungals can inhibit hepatic metabolism (CYP3A4) and raise plasma levels of many medications including some Androgen / anabolic steroid agents. Rifampicin has the opposite effect, accelerating metabolism. Most penicillins, cephalosporins, fluoroquinolones and tetracyclines have no clinically meaningful interaction with Testosterone at 1%, 1.62%.
Practical guidance
According to the prescribing information for Testosterone, an antibiotic course should be reviewed by the prescriber or pharmacist for known interactions before Testosterone is co-administered. Adjusted 1%, 1.62% dosing or temporary substitution is sometimes preferred for the duration of the antibiotic course.
Frequently asked questions
Can I take Testosterone during an antibiotic course? ▾
For most common antibiotics, yes. A few classes — notably macrolides and azole antifungals — alter how Testosterone is metabolised and may need a temporary 1%, 1.62% adjustment. The prescribing pharmacist should review any new antibiotic against the existing Testosterone regimen.
Will antibiotics make Testosterone stop working? ▾
Most antibiotics do not affect Testosterone efficacy. Rifampicin and a few others can lower Testosterone levels and reduce effect; in those cases the prescriber may adjust the dose during and shortly after the antibiotic course.
Products containing Testosterone
More on Testosterone
- With alcoholTestosterone and alcohol — is it safe to drink?
- With foodShould Testosterone be taken with food?
- Side effectsTestosterone side effects: common, rare and warning signs
- Dosage guideTestosterone dosage guide: how much to take and when
- OnsetHow fast does Testosterone start working?
- DurationHow long does Testosterone last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.