PDE5 inhibitor
How to take Tadalafil tablets correctly
How a tablet is swallowed matters for absorption, gastric tolerance and avoiding oesophageal irritation. Tadalafil (Tadalafil) at 20mg, 2.5mg, 5mg, 10mg is straightforward to take for most adults but a few practical points reduce variability and minimise local side effects.
Standard administration of Tadalafil
Most tablet, sublingual tablet, soft gelatin capsule of Tadalafil are taken whole with a full glass of water (about 200 mL). Sitting or standing upright for 10–15 minutes after dosing reduces the risk of the tablet lodging in the oesophagus and causing local irritation. Sufficient water carries the medication into the stomach where dissolution and absorption begin.
Practical tips and what to avoid
According to the prescribing information for Tadalafil, taking Tadalafil with too little water or while lying down increases oesophageal exposure and can cause heartburn-like irritation in susceptible users. Lukewarm or cool water is preferable to very hot water. Tablets should not be chewed unless explicitly authorised by the prescriber for the formulation; Tadalafil selectively inhibits PDE5, the enzyme responsible for breaking down cyclic guanosine monophosphate in the corpus cavernosum and other vascular smooth muscle.
Frequently asked questions
How much water should I take with Tadalafil? ▾
A full glass — about 200 mL — is the standard recommendation for Tadalafil at 20mg, 2.5mg, 5mg, 10mg. Less water increases the risk of the tablet sticking on the way down and causing local irritation.
Can I take Tadalafil without water? ▾
It is not advisable. Tablets without water can lodge in the oesophagus and cause local irritation; some formulations require water for proper dissolution. Always take Tadalafil with adequate water unless the formulation explicitly says otherwise.
Products containing Tadalafil
More on Tadalafil
- With alcoholTadalafil and alcohol — is it safe to drink?
- With foodShould Tadalafil be taken with food?
- Side effectsTadalafil side effects: common, rare and warning signs
- Dosage guideTadalafil dosage guide: how much to take and when
- OnsetHow fast does Tadalafil start working?
- DurationHow long does Tadalafil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.