Cialis Professional (Sublingual Tadalafil 20mg)
Cialis Professional is a sublingual formulation of tadalafil 20mg, designed to begin acting more quickly than a swallowed tablet by being absorbed through the mucosa under the tongue. For adult men with erectile dysfunction; same 36-hour effect window.
- Active ingredients
- Tadalafil
- Manufacturer
- Eli Lilly
- Dosage forms
- sublingual tablet
- Available dosages
- 20mg
- Category
- Erectile Dysfunction (ED)
What is it?
Cialis Professional is a sublingual formulation of tadalafil marketed for adult men with erectile dysfunction. The tablet is placed under the tongue, where it dissolves and is absorbed through the oral mucosa, bypassing the gastrointestinal route of conventional tablets. The product positions itself as a faster-onset alternative for users who want a shorter delay between dose and effect, while preserving tadalafil's characteristic 36-hour effect window. The active molecule and overall safety profile match standard tadalafil products.
Active ingredients
Each Cialis Professional tablet contains 20mg of tadalafil. The selective PDE5 inhibition mechanism is identical to other tadalafil products, but the route of absorption differs. According to product literature, sublingual administration can shorten the time to peak plasma concentration relative to swallowing, which translates into a slightly earlier onset. The chemical structure, half-life and metabolic profile of tadalafil itself are unchanged.
Forms and dosages
Cialis Professional is supplied as 20mg sublingual tablets that should be placed under the tongue and allowed to dissolve completely without swallowing. The recommended dose is one tablet approximately 15 to 30 minutes before planned sexual activity, taken without water. Maximum dosing is one tablet per 24 hours. Eating, drinking and smoking should be avoided for several minutes after dosing to allow full mucosal absorption.
Indications
Cialis Professional is intended for adult men with erectile dysfunction. It is not indicated for women, paediatric patients or men without a clinical diagnosis. According to general prescribing principles for tadalafil, the cardiovascular fitness and current medication list of the patient should be reviewed before use. The 20mg-only presentation is not suited to patients who would normally require lower starting doses for tolerability reasons.
How it works
Tadalafil inhibits PDE5 in penile tissue and other vascular smooth muscle, allowing cyclic GMP produced during sexual arousal to accumulate, relaxing smooth muscle and increasing blood inflow. The sublingual route delivers the molecule directly into systemic circulation through the oral mucosa, partially bypassing first-pass hepatic metabolism. According to product literature, this can shorten onset of action to 15 to 30 minutes, while preserving the long 36-hour effect window characteristic of tadalafil.
Frequently asked questions
How is Cialis Professional different from regular Cialis? ▾
Both contain tadalafil 20mg and produce the same therapeutic effect with the same 36-hour window. The difference is the route of administration: Cialis Professional is taken sublingually (dissolved under the tongue), while regular Cialis is swallowed whole. Sublingual administration can shorten the onset of action to approximately 15 to 30 minutes, according to product literature, because absorption through the oral mucosa bypasses part of the gastrointestinal route.
How do I take a sublingual tablet correctly? ▾
Place the Cialis Professional tablet under your tongue and let it dissolve completely without swallowing or chewing. Avoid drinking, eating or smoking for several minutes to allow full absorption through the oral mucosa. The recommended timing is 15 to 30 minutes before sexual activity. According to product literature, swallowing the tablet whole reduces the speed advantage of the sublingual format.
Does the sublingual form change the 36-hour window? ▾
No. The half-life of tadalafil — approximately 17.5 hours — is determined by metabolism after absorption, not by the route of administration. The 36-hour effect window after a single dose is preserved in the sublingual form. What changes is only the speed of onset, with sublingual reaching peak concentration somewhat earlier than swallowed tablets, according to product literature.
Is sublingual tadalafil safer than swallowed tadalafil? ▾
The systemic exposure and overall safety profile are comparable at the same dose. The sublingual route may slightly reduce hepatic first-pass metabolism, but does not change contraindications such as concurrent use of nitrates or severe cardiovascular disease. According to general prescribing principles for tadalafil, the same medical evaluation should precede use of either form.
What contraindications apply to Cialis Professional? ▾
Contraindications match those of all tadalafil products: concurrent use of organic nitrates or guanylate cyclase stimulators is contraindicated due to severe hypotension risk. Caution is required in patients with severe cardiovascular disease, recent stroke or heart attack, severe hepatic impairment and known hypersensitivity to tadalafil. According to the prescribing information, full medical history must be reviewed before initiation.
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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.