PDE5 inhibitor
Tadalafil when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Tadalafil (Tadalafil) at 20mg, 2.5mg, 5mg, 10mg may need to be continued, switched, or stopped before conception, depending on the active ingredient Tadalafil and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Tadalafil
According to the prescribing information for Tadalafil, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some PDE5 inhibitor medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Tadalafil selectively inhibits PDE5, the enzyme responsible for breaking down cyclic guanosine monophosphate in the corpus cavernosum and other vascular smooth muscle.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Tadalafil has any documented effect on fertility depends on Tadalafil; the prescribing information notes any data. Anyone trying to conceive should discuss Tadalafil with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Tadalafil before trying to conceive? ▾
It depends on Tadalafil and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Tadalafil affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in PDE5 inhibitor affect sperm parameters or libido; others have no documented effect. The prescribing information for Tadalafil states what is known. If conception is delayed, a semen analysis can clarify whether Tadalafil is contributing.
Products containing Tadalafil
More on Tadalafil
- With alcoholTadalafil and alcohol — is it safe to drink?
- With foodShould Tadalafil be taken with food?
- Side effectsTadalafil side effects: common, rare and warning signs
- Dosage guideTadalafil dosage guide: how much to take and when
- OnsetHow fast does Tadalafil start working?
- DurationHow long does Tadalafil last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.