Selective serotonin reuptake inhibitor (SSRI)
Paroxetine and surgery: what to do before and after
Surgery raises specific medication-management questions, and getting the answer right matters because both unintended drug interactions during anaesthesia and abrupt discontinuation of important chronic therapies carry risk. Whether Paroxetine (Paroxetine) needs to be stopped before surgery, continued through, or paused for a defined window depends on Paroxetine and the type of procedure.
Before-surgery decision
For most chronic medications including many Selective serotonin reuptake inhibitor (SSRI) agents, the surgical team or anaesthetist makes the stop-or-continue decision during pre-op assessment. Considerations include bleeding risk, anaesthesia interactions, the urgency of the underlying condition and the type of procedure. According to most guidelines, surprises are avoided by listing all medications including Paroxetine at 10mg, 20mg, 30mg, 40mg on the pre-op form.
After surgery
Post-operative resumption of Paroxetine depends on the surgical course, the medication's impact on recovery (e.g. wound healing, gastric tolerance, mobility) and any new prescriptions added after surgery. Paroxetine selectively inhibits the serotonin reuptake transporter, increasing serotonin availability at the synapse. Resuming on schedule is usually the goal as soon as oral intake and clinical stability allow.
Frequently asked questions
Do I need to stop Paroxetine before surgery? ▾
It depends on Paroxetine and the procedure. The pre-op assessment is where this is decided, ideally a week or more before surgery. Bring the full medication list including Paroxetine at 10mg, 20mg, 30mg, 40mg so the team can advise.
When can I restart Paroxetine after surgery? ▾
Resumption timing depends on the procedure, the recovery course and any interactions with new postoperative medications. Many patients restart Paroxetine on the day of discharge or earlier; some need a longer pause. The surgical team or prescriber confirms the timing.
Products containing Paroxetine
More on Paroxetine
- With alcoholParoxetine and alcohol — is it safe to drink?
- With foodShould Paroxetine be taken with food?
- Side effectsParoxetine side effects: common, rare and warning signs
- Dosage guideParoxetine dosage guide: how much to take and when
- OnsetHow fast does Paroxetine start working?
- DurationHow long does Paroxetine last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.