Atypical antidepressant (NaSSA)
How Mirtazapine affects libido and sex drive
Libido and sex drive are commonly affected by medications, sometimes intentionally (e.g. ED therapies) and sometimes as an unwelcome side effect. Mirtazapine (Mirtazapine) may or may not affect libido depending on Mirtazapine; this page outlines what is documented at 7.5mg, 15mg, 30mg, 45mg and what users typically report.
Documented effects of Mirtazapine on libido
Some medications in Atypical antidepressant (NaSSA) are designed specifically to affect sexual function; for those, libido changes are expected and central to the indication. Others have libido changes as side effects of altered hormones, mood, energy or autonomic function. According to the prescribing information for Mirtazapine, the documented frequency varies and is listed in the side-effect profile.
Managing libido changes
For unwanted libido suppression, the right response often depends on whether the issue is the medication itself, the underlying condition, fatigue, or relationship factors. Mirtazapine antagonises presynaptic α2-adrenergic autoreceptors and heteroreceptors, increasing noradrenaline and serotonin release. A dose review, a switch within the same class, or addressing other contributors are all reasonable strategies and should be discussed with the prescriber rather than self-managed by stopping Mirtazapine at 7.5mg, 15mg, 30mg, 45mg.
Frequently asked questions
Does Mirtazapine lower libido? ▾
Some users on Mirtazapine report reduced libido, some report no change, and a few — particularly on indications targeting sexual function — report improvement. Whether this happens depends on Mirtazapine and individual factors. The prescriber can review options if libido changes are persistent or distressing.
Can libido recover after stopping Mirtazapine? ▾
For most users, libido changes attributable to Mirtazapine resolve within weeks of stopping the medication, though the timeline varies by active ingredient and individual. Persistent changes after stopping warrant medical evaluation, as the underlying condition may be the contributing factor.
Products containing Mirtazapine
More on Mirtazapine
- With alcoholMirtazapine and alcohol — is it safe to drink?
- With foodShould Mirtazapine be taken with food?
- Side effectsMirtazapine side effects: common, rare and warning signs
- Dosage guideMirtazapine dosage guide: how much to take and when
- OnsetHow fast does Mirtazapine start working?
- DurationHow long does Mirtazapine last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.