Atypical antidepressant (NaSSA)
Mirtazapine when planning pregnancy
For couples trying to conceive, every chronic medication deserves a careful pre-pregnancy review. Mirtazapine (Mirtazapine) at 7.5mg, 15mg, 30mg, 45mg may need to be continued, switched, or stopped before conception, depending on the active ingredient Mirtazapine and the indication. The right answer is rarely the same for everyone and rarely "just stop the medication."
Pre-conception review of Mirtazapine
According to the prescribing information for Mirtazapine, the pre-conception decision balances the risk of the medication during pregnancy against the consequences of leaving the underlying condition untreated. Some Atypical antidepressant (NaSSA) medications are continued safely through pregnancy; others are switched to safer alternatives before conception or in early pregnancy. Mirtazapine antagonises presynaptic α2-adrenergic autoreceptors and heteroreceptors, increasing noradrenaline and serotonin release.
Effect on fertility itself
Some medications affect fertility directly — by altering ovulation, sperm parameters, hormonal balance or libido. Whether Mirtazapine has any documented effect on fertility depends on Mirtazapine; the prescribing information notes any data. Anyone trying to conceive should discuss Mirtazapine with the prescriber and a fertility specialist if conception is taking longer than expected.
Frequently asked questions
Should I stop Mirtazapine before trying to conceive? ▾
It depends on Mirtazapine and the indication. For some medications the answer is yes — switch to a safer alternative weeks before conception. For others, continuation is safe and preferable. The prescriber decides based on the full clinical picture.
Does Mirtazapine affect male fertility? ▾
Effects on male fertility depend on the active ingredient. Some medications in Atypical antidepressant (NaSSA) affect sperm parameters or libido; others have no documented effect. The prescribing information for Mirtazapine states what is known. If conception is delayed, a semen analysis can clarify whether Mirtazapine is contributing.
Products containing Mirtazapine
More on Mirtazapine
- With alcoholMirtazapine and alcohol — is it safe to drink?
- With foodShould Mirtazapine be taken with food?
- Side effectsMirtazapine side effects: common, rare and warning signs
- Dosage guideMirtazapine dosage guide: how much to take and when
- OnsetHow fast does Mirtazapine start working?
- DurationHow long does Mirtazapine last?
The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.