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Long-acting beta-2 agonist (LABA)

Formoterol with vitamins, minerals and herbal supplements

Supplements are widely used and rarely disclosed to the prescriber, which makes them a common source of unrecognised interactions with Formoterol (Formoterol). Many supplements are inert or harmless, but a small number — particularly herbal extracts and high-dose vitamins — can affect how Formoterol works at 80/4.5 mcg, 160/4.5 mcg, 200/6 mcg, 400/12 mcg.

High-priority supplement interactions

St John's Wort is the herbal supplement most often flagged for interactions because it strongly induces CYP3A4 and reduces plasma levels of many medications including several Long-acting beta-2 agonist (LABA) agents. Grapefruit-extract supplements work in the opposite direction. High-dose vitamin K affects anticoagulants. Calcium and iron can chelate certain antibiotics.

Practical disclosure

According to the prescribing information for Formoterol, the medication list reviewed by the pharmacist should always include supplements. Most multivitamins at standard doses do not interact meaningfully with Formoterol at 80/4.5 mcg, 160/4.5 mcg, 200/6 mcg, 400/12 mcg, but anything herbal, anything single-ingredient at high dose, and anything new started recently is worth flagging.

Frequently asked questions

Are vitamins safe with Formoterol?

Standard-dose multivitamins are usually fine with Formoterol at 80/4.5 mcg, 160/4.5 mcg, 200/6 mcg, 400/12 mcg. High-dose single vitamins (e.g. vitamin K, large doses of vitamin E) can interact with specific medication classes; the pharmacist confirms whether these matter for Formoterol.

Should I tell the pharmacist about herbal supplements?

Yes — particularly St John's Wort, ginseng, ginkgo, garlic extract and any concentrated herbal formulation. Several of these have meaningful interactions with prescription medications including some agents in the Long-acting beta-2 agonist (LABA) class.

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The information on this website is provided for reference and educational purposes only. It does not replace consultation with a qualified healthcare professional.